NIACYNAMID rejuvenating vitamin
Niacinamide is one of two forms of vitamin B3 (the other is nicotinic acid), acting as a precursor of NADH and NADPH coenzymes, which are involved in many key biochemical reactions.
In particular, they play an important role in glucose metabolism, energy production in cells, lipid synthesis in the skin and many others. The level of both coenzymes decreases with age and external administration of niacinamide seems to reverse this decrease.
In addition, niacinamide is one of the safer ingredients, extremely stable, well-tolerated in formulations, even at high concentrations. It has a very wide spectrum of action, suitable for almost any skin type.
Niacinamide can be used in rejuvenating therapy to reduce fine lines and wrinkles, even out skin tone by reducing skin discoloration and yellowness.
Numerous clinical studies have shown the positive effect of moisturizing preparations containing niacinamide on the reduction of fine lines and wrinkles in aging skin. The randomized study involved 50 women who for 12 weeks applied half a face cream containing 5% niacinamide compared to placebo, applied to the other side of the face. There was a reduction in wrinkle depth with p = 0.06 at week 8 and 0.0005 at week 12.
Vitamin B3 also has antioxidant and anti-inflammatory properties, which means that it has a positive effect on reducing moderate acne, reducing its symptoms in the form of excessive secretion of sebum and enlarged pores.
Two studies were carried out comparing the relationship between excessive sebum secretion and enlarged pores and the action of a moisturizer containing 2% niacinamide. The results of both studies, conducted on a group of Caucasian and Japanese women, showed that after 4 weeks of using the cream 2x a day, both sebum production and pore size decreased compared to baseline parameters. An improvement in skin elasticity was also observed.
Recent studies have shown that the use of moisturizers containing niacinamide during retinoid therapy reduces its side effects and increases the effects, which means that the use of niacinamide has an indirect positive effect on collagen production.
Vitamin B3, offered in our store, has an extremely low content of nicotinic acid - 0.017%, so it does not cause vasodilation and can be safely used for vascular skin.
Niacinamide is such a stable substance that it can be combined with acids and vitamin C.
How it works:
• moisturizes dry, oily skin but with signs of dehydration
• soothes irritations, reduces flaking
• rebuilds the skin's protective barrier
• anti-aging - reduces wrinkles and age-related skin disorders like discoloration, age spots, enlarged pores,
• reduces the sensitivity of the skin in the case of rosacea
• soothes acne, reduces enlarged pores
• soothes and heals minor inflammatory changes
• supportively when using retinoids and acids
• face and neck preparations
• body preparations
• hand preparations - removes roughness of the epidermis, reduces redness and the effect of chapped hands
• scalp tonics for itchy scalp, with dandruff
• for ready-made products - mix with a small amount of distilled water, hydrolate or ready-made cosmetics until the niacinamide dissolves and mix with the rest of the cream or serum
INCI: Niacinamide Recommended concentration: 2 - 5% Bulk weight: 0.58g / ml Physicochemical properties: *white powder with a crystalline structure *no smell *soluble in water, ethyl alcohol Technical recommendations: *stable in acidic environment in the range of pH 3 - 7.5 *resistant to heating up to ca 85oC *store at room temperature
- Ultrasound enhanced skin-lightening effect of vitamin C and niacinamide.
- Hakozaki T, Takiwaki H, Miyamoto K, Sato Y, Arase S. Department of Dermatology, School of Medicine, University of Tokushima, Tokushima, Japan. firstname.lastname@example.org